Search our team at AdventHealth Research Institute
-
Prospective Registry for Colorectal Cancer: International Watch and Wait Database
This study is not currently enrolling.Associated Conditions: Colorectal CancerResearch Area: Cancer ResearchThis research is being done as part of a larger international database for 'Watch and Wait' rectal cancer patients. Currently, the 'Watch and Wait' treatment shows promising results worldwide, however...
-
NCT04793958
A Randomized PHase 3 Study of MRTX849 in Combination with Cetuximab Versus Chemotherapy in Patients with Advanced Colorectal Cancer with KRAS G12C Mutation with Disease Progression On or After Standard First-Line Therapy
This study is currently enrolling.Associated Conditions: Colorectal CancerResearch Area: Cancer ResearchResearch Location: Orlando, FloridaThis is a study involving an investigational (experimental) drug called MRTX849, being developed by Mirati Therapeutics, Inc., which is the company that provides MRTX849 study drug and is funding and...
-
NCT05610163
THE JANUS RECTAL CANCER TRIAL: A RANDOMIZED PHASE II TRIAL TESTING THE EFFICACY OF TRIPLET VERSUS DOUBLET CHEMOTHERAPY TO ACHIEVE CLINICAL COMPLETE RESPONSE IN PATIENTS WITH LOCALLY ADVANCED RECTAL CANCER
This study is currently enrolling.Associated Conditions: Colorectal CancerResearch Area: Cancer ResearchResearch Location: Orlando, FloridaTo evaluate and compare the cCR rates in patients with locally advanced rectal cancer treated with neoadjuvant LCRT followed by neoadjuvant mFOLFIRINOX versus neoadjuvant LCRT followed by neoadjuvant...
-
NCT01515787
A Phase II/III of Neoadjuvant FOLFOX with Selective Use of Combined Modality Chemoradiation versus Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection with Total Mesorectal Excision (PROSPECT)
This study is currently enrolling.Associated Conditions: Colorectal CancerResearch Area: Cancer ResearchResearch Location: Orlando, Florida[$] [Abbreviated - Closed] The purpose of this study is to compare the effects, both good and bad, of the standard treatment of chemotherapy and radiation to chemotherapy using a combination regimen...
-
NCT05174169
NRG-GI008: COLON ADJUVANT CHEMOTHERAPY BASED ON EVALUATION OF RESIDUAL DISEASE (CIRCULATE-US)
This study is currently enrolling.Associated Conditions: Colorectal CancerResearch Area: Cancer ResearchResearch Location: Orlando, FloridactDNA-ve Cohort (Arms 1 + 2): Phase II: To compare time to ctDNA (+ve) status in ctDNA (-ve) cohort following resection of stage III colon cancer treated with immediate vs delayed (based on serial...