Search our team at AdventHealth Research Institute
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Mother Providing Recorded Voice to Her Preterm Infant in Incubator Improves Her Own Grief and Emotional Status
This study is not currently enrolling.Associated Conditions: NeonatalResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaStudies have shown that infants prefer the sound of their mother's voice above all others. After 2 weeks (or 14 days) of life, we would like to begin playing a recording to babies of their mother's...
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NCT03519945
A Phase 3, Multicenter, Open-Label Extension Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Patients with Moderately to Severely Active Ulcerative Colitis
This study is not currently enrolling.Associated Conditions: ColonResearch Area: Digestive Health and SurgeryResearch Location: Orlando, FloridaThis study is being done to help answer the following research questions: (a) How mirikizumab, an investigational drug, could help people with ulcerative colitis over time; (b) How safe long-term use...
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NCT04166409
A Phase 3 Randomized Non-Inferiority Study of Carboplatin and Vincristine versus Selumetinib (NSC# 748727, IND# 77782) in Newly Diagnosed or Previously Untreated Low-Grade Glioma (LGG) not associated with BRAFV600E Mutations or Systemic Neurofibromatosis Type 1 (NF1)
This study is not currently enrolling.Associated Conditions: Brain CancerResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaThis study looks at how well a drug called selumetinib works when given to children and young adults with LGG. The study doctors want to see if selumetinib works as well as CV for getting rid of or...
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NCT04284774
NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 subprotocol of Tipifarnib in Patients with Tumors Harboring HRAS Genomic Alterations
This study is not currently enrolling.Associated Conditions: Cancer, Multiple Tumor TypesResearch Area: Cancer ResearchResearch Location: Orlando, FloridaThis is a Phase 2 study of a study drug called tipifarnib. The main goal of the study is to find out what effect, good and/or bad effects the study drug tipifarnib may have on your tumor. A second...
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NCT04195555
APEC1621K NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of AG-120 (Ivosidenib) in Patients with Tumors Harboring IDH1 Mutations.
This study is not currently enrolling.Associated Conditions: Cancer, Multiple Tumor TypesResearch Area: Cancer ResearchResearch Location: Orlando, FloridaThe main goal is to find out what effect, good and/or bad effects AG-120 (ivosidenib) on your tumor. A second goal of the study is to evaluate side effects that might be caused by AG-120 (ivosidenib)...
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NCT03871257
A Phase 3 Randomized Study of Selumetinib (IND# 77782) versus Carboplatin/Vincristine in Newly Diagnosed or Previously Untreated Neurofibromatosis Type 1 (NF1) Associated Low-Grade Glioma (LGG)
This study is not currently enrolling.Associated Conditions: Brain CancerResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaThe overall goals of this study are to see if selumetinib works just as well as the standard treatment of carboplatin/vincristine (CV) for subjects with NF1-associated LGG, and to see if selumetinib...
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Routine versus No Assessment of Gastric Residual Volumes in Very Low Birth Weight Infants Receiving Enteral Feeding via Intermittent Feeding Tubes: A Randomized Controlled Trial
This study is not currently enrolling.Associated Conditions: NeonatalResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaPre term infants require feeding tubes when they start receiving feeds. Once the volume of milk increases, the current practice in our Neonatal Intensive Care Unit (NICU) is to attach a syringe to the...
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NCT04321031
Prospective Observational Study to Assess Outcomes in Pediatric Liver Transplant Recipients
This study is not currently enrolling.Associated Conditions: TransplantResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaThe purpose of the study is to collect scientific data on pediatric liver transplantation to learn more about how children do after liver transplant. Collecting this data is expected to help...
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Robotic-assisted Laparoscopic Varicocelectomy in the Pediatric population
This study is not currently enrolling.Associated Conditions: SurgeryResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaThe aim of this study is to describe outcomes and complications in robotic varicocelectomy in the pediatric population.
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Outcomes and Complications of Pediatric Robotic Ureteral Reimplantation
This study is not currently enrolling.Associated Conditions: SurgeryResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaThe aim of this to describe outcomes and complications in robotic ureteral reimplantation in the pediatric population.
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NCT03220035
NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of Vemurafenib in Patients with Tumors Harboring BRAF V600 Mutations
This study is not currently enrolling.Associated Conditions: Cancer, All Tumor TypesResearch Area: Cancer ResearchResearch Location: Orlando, FloridaYou are being asked to participate in this study because you have relapsed or refractory tumor without a proven treatment strategy for cure. The main goal is to test any good and bad effects of the...
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NCT03213652
NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of Ensartinib in Patients with Tumors Harboring ALK or ROSI Genomic Alterations
This study is not currently enrolling.Associated Conditions: Multiple Tumor TypesResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaYou are being asked to participate in this study because you have a relapsed or refractory tumor without a proven treatment strategy for cure. The main goal of this study is to test any good and bad...