Search our team at AdventHealth Research Institute
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NCT03213691
NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of Selumetinib (AZD6244 Hydrogen Sulfate)in Patients with Tumors Harboring Activating MAPK Pathway Mutations
This study is not currently enrolling.Associated Conditions: Multiple Tumor TypesResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaThe main goal is to test any good and bad effects of the study drug selumetinib (AZD6244 hydrogen sulfate) on your tumor. A second goal of the study is to evaluate side effects that might be caused by...
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NCT03213678
NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of LY3023414 in Patients with Solid Tumors
This study is not currently enrolling.Associated Conditions: Cancer, Multiple Tumor TypesResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaThis is a Phase 2 study of a drug called LY3023414. In a Phase 2 study, the goal is to find out what effects, good and/or bad, a drug has on your tumor or type of cancer.
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NCT03295734
ACES: Ace Inhibitors Combined with Exercise for Hypertensive Seniors
This study is not currently enrolling.Associated Conditions: Aging-Nutrition and Physical ActivityResearch Area: Translational ResearchResearch Location: Orlando, FloridaThe purpose of this research study is to see if regular exercise when combined with one of three commonly used high blood pressure medications can improve the physical abilities of older adults to...
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NCT03213704
NCI-COG Pediatric Match (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of LOXO-101 (Larotrectinib) in Patients with Tumors Harboring Actionable NTRK Fusions
This study is not currently enrolling.Associated Conditions: Cancer, Companion StudyResearch Area: Cancer ResearchResearch Location: Orlando, FloridaThe overall goal of this study is to test any good and bad effects of the study drug LOXO-101 (larotrectinib) on your tumor.
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NCT04164966
HONEY: Development of novel biomarkers for the early diagnosis of type 1 diabetes
This study is not currently enrolling.Associated Conditions: Diabetes-MechanismsResearch Area: Translational ResearchResearch Location: Orlando, FloridaType 1 Diabetes (T1D) or Juvenile diabetes is an autoimmune disease projected to affect 5 million people, including 600,000 children in US alone, by the year 2050. There is currently no cure or...
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NCT03067181
A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients with Germ Cell Tumors
This study is not currently enrolling.Associated Conditions: Brain CancerResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaLow Risk Subjects (Age <50 Years): The overall goal is to see if monitoring subjects with low risk germ cell tumors after their tumor is removed is as effective as following surgery with chemotherapy...
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NCT03233711
A Randomized Phase II Study of Nivolumab after Combined Modality Therapy (CMT) in High Risk Anal Cancer
This study is not currently enrolling.Associated Conditions: Anal CancerResearch Area: Cancer ResearchResearch Location: Orlando, FloridaThe purpose of this study is to find if adding the study drug, nivolumab (also known as OPDIVO), after standard chemotherapy {(mitomycin-C and 5-fluorouracil 5(-RU) or capecitabine) or 5-FU and...
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NCT03960827
MoTrPAC: Molecular Transducers of Physical Activity Consortium
This study is not currently enrolling.Associated Conditions: ExerciseResearch Area: Translational ResearchResearch Location: Orlando, FloridaThe goal of the Molecular Transducers of Physical Activity Consortium (MoTrPAC) is to assess molecular changes that occur in response to physical activity (PA). To achieve this aim, a mechanistic...
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Florida Neonatal Neurologic Network: A Retrospective Data Bank
This study is not currently enrolling.Associated Conditions: NeonatalResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaThe project will involve the creation of the Florida Neonatal Neurologic Network. This network will consist of major academic and private hospitals in North-Central Florida linked together with the...
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Establishment of the Pediatric Obesity Weight Evaluation Registry
This study is not currently enrolling.Associated Conditions: Obesity, Weight ManagementResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaThe purpose of this study is to create a bank of information and outcomes for patients who are part of a weight management program using data collected from medical records.
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Children's Hospitals Neonatology Consortium (CHNC): Data Sharing and Quality Improvement Initiative
This study is not currently enrolling.Associated Conditions: NeonatalResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaThe complex high acuity-patient population seen in tertiary NICU's located in major children's hospitals across the nation is a unique predominately referral population, not seen in most NICU's...
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Multicenter, prospective, non-interventional follow-up of braided sublaminar bands for pediatric scoliosis
This study is not currently enrolling.Associated Conditions: SurgeryResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaThis research is being done to report clinical and radiographic outcomes of braided sublaminar bands, and to assess the safety of this FDA approved Jazz system.