Search our team at AdventHealth Research Institute
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NCT05463731
A Study of Remternetug Versus Placebo in Early Alzheimer’s Disease Participants at Risk for Cognitive and Functional Decline
This study is currently enrolling.Research Area: Clinical Neuroscience ResearchResearch Location: Orlando, FloridaThis study is looking to assess the effect of remternetug versus
placebo on time to clinically meaningful
progression in participants with early AD. -
NCT06602141
Assessments of Adipogenesis, Lipid Turnover and Cellular Composition in Adipose Tissue in Response to Endurance Exercise
This study is currently enrolling.Associated Conditions: ExerciseResearch Area: Translational Research for Metabolism and DiabetesResearch Location: Orlando, FloridaStudy Purpose: The purpose of this research study is to study the effects of endurance exercise training on adipose (fat) tissue quality and insulin resistance in people with obesity.
To be enrolled...
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NCT05761171
AALL2121: A Phase 2 Study of SNDX-5613 in Combination with Chemotherapy for Patients with Relapsed or Refractory KMT2A-Rearranged Infant Leukemia
This study is currently enrolling.Associated Conditions: LeukemiaResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThe overall goal of this study is to determine the safety and best dose of the drug SNDX-5613 for young children when given in combination with chemotherapy, and to see if this treatment will improve...
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Targeting Network Dysfunction in Apathy of Late-life Depression Using Digital Therapeutics
This study is currently enrolling.Research Area: Clinical Neuroscience ResearchResearch Location: Orlando, FloridaThe purpose of this study is to examine whether a targeted and remotely-delivered Digital Cognitive Training (DCT) intervention can modulate the network connectivity of depressed apathetic persons and...
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Efficacy of the AAP discharge recommendations to decrease emergency room visit within 14 days after discharge in well late preterm newborns
This study is currently enrolling.Associated Conditions: NeonatalResearch Area: Pediatric Research and Clinical TrialsResearch Location: Celebration, Florida -
External Evaluation Plan: User Evaluation of the Next Generation CardioLab EP Recording System with the Prucka 3 Digital EP Amplifier
This study is currently enrolling.Research Area: Heart, Lung and Vascular ResearchResearch Location: Celebration, FloridaThe current CardioLab system is cleared by the FDA for use on patients of all ages when a physician determines that a patient would benefit from an electrophysiology procedure. CardioLab can be used...
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NCT06203600
Randomized Phase II/III Trial of 2nd Line Nivolumab + Paclitaxel + Ramucirumab versus Paclitaxel + Ramucirumab in Patients with PD-L1 CPS ? 1 Advanced Gastric and Esophageal Adenocarcinoma (PARAMUNE)
This study is currently enrolling.Associated Conditions: Esophageal CancerResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThis study is being done to answer the following questions: Can adding a drug to the usual treatment for advanced stomach and esophageal cancers make it less likely that these cancers will grow or...
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Evaluating the Efficacy of the Full Plate Living Program: A Cardiology Clinic-based Intervention in Winter Park, FL
This study is currently enrolling.Research Area: Heart, Lung and Vascular ResearchResearch Location: Winter Park, FloridaThe primary objective of this study is to evaluate the impact of the Full Plate Living Program, developed by the Ardmore Institute of Health, on patient nutrition knowledge, diet, and lifestyle. The...
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rhPSMA-7.3(18F)-PET scan to detect prostate cancer in patients with early PSA recurrence.
This study is currently enrolling.Associated Conditions: Prostate CancerResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThe research is being done at the Radiology Nuclear Medicine Department of AdventHealth Orlando and Celebration. Patients are instructed to drink water prior to administration of flotufolastat F-18 to...
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NCT05940857
Sponsor-Initiated OCS Liver Perfusion (OLP-II) Registry
This study is currently enrolling.Research Area: Transplant ResearchResearch Location: Orlando, FloridaThe objective of the sponsor-initiated OLP-II Registry is to collect data on the post-transplant clinical outcomes of donor livers preserved and assessed on OCS Liver System and to document...
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NCT05858164
An open-label, phase 1, first-in-human, dose escalation and expansion study to evaluate the safety, tolerability, maximum tolerated or administered dose, pharmacokinetics, pharmacodynamics, and tumor response profile of the diacylglycerol kinase alpha inhibitor (DGKai) BAY 2862789 in participants with advanced solid tumors
This study is currently enrolling.Associated Conditions: Metastatic Solid TumorsResearch Area: Clinical Cancer ResearchResearch Location: Celebration, FloridaThis study is being done to learn more about a new drug called BAY 2862789, an inhibitor of diacylglycerol kinase alpha (DGKα). BAY 2862789 is an immunotherapy drug that has been developed to activate...
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NCT04073563
Prospective, Randomized, Controlled, Blinded Pivotal Study In Subjects Undergoing A Transforaminal Lumbar Interbody Fusion (TLIF) At One Or Two Levels Using Infuse™ Bone Graft With an Intervertebral Body Fusion Device and Posterior Supplemental Fixation For The Treatment Of Symptomatic Degenerative Disease Of The Lumbosacral Spine
This study is currently enrolling.Research Area: Clinical Neuroscience ResearchResearch Location: Orlando, FloridaThe purpose of this study is to evaluate the Infuse™ Bone Graft in combination with other spinal devices and autograft bone (your own bone) to see if it is safe and effective when used in a TLIF...