Critical Care Research Overview
Our world-class team of researchers, clinical scientists and support staff is equipped to meet a wide array of research needs ranging from early-phase PoC/PoM trials to Phase I-III trials as well as RWE and HEOR.
Our research services highlights include: PIs with extensive research and publications experience; CDA execution within 24 hours; access to local IRB with the ability to use Central IRB; IRB approval completed within two weeks of submission; MSA to FPI turnaround of five days (COVID-19 trials); remote monitoring with access to our electronic medical record; CRCs’ have experience with most EDC systems; and high staff retention rates of our RAs and RNs.
Meet Our Team
Featured Clinical Trials
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NCT04360096
Inhaled RLF-100 for the Treatment of Severe COVID-19 without respiratory failure
This study is not currently enrolling.Associated Conditions: COVIDResearch Area: Critical Care ResearchThe purpose of this research is to: To show whether the study drug RLF-100 along with standard of care is better than standard of care alone in preventing progression from Severe COVID-19 to Critical...
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NCT04805970
RECODE: Researching Covid Outcomes in Diabetes
This study is not currently enrolling.Research Area: Translational Research for Metabolism and DiabetesResearch Location: Orlando, FloridaWe invite you to take part in a research study because you have previously had a confirmed diagnosis for COVID-19 (the new coronavirus) disease. You have recovered, or are recovering from this disease...
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Fighting Critical Illness Together
The COVID-19 pandemic represented an unprecedented challenge for our hospitals and community. We rose to the challenge to meet the demands of treatment options and clinical trials. We engaged operational teams in the inpatient and outpatient settings to include medical oversight by a Physician Principal Investigator and an APRN/PA with prior infectious disease experience. Clinical research coordinators, medical assistants, pharmacists, lab techs and program management support rounded out these multidisciplinary collaborative teams. The heroic efforts of our teams are a testament to our dedication and ability to work under pressure to keep our communities safe from a wide range of critical illnesses.
- PowerBI-Pandemic Board
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To aid operations in the containment, mitigation, surge and post-surge phases of the pandemic, AdventHealth developed the COVID-19 Pandemic Tracker, where all orders for COVID-19 tests and their results are curated in a big data server, allowing for near real-time reporting. AdventHealth collects data resulting from nasopharyngeal and saliva PCR testing, serology and rapid antigen testing in our inpatient, outpatient and ED facilities. COVID-19 testing volumes, positive patient census and intervention utilization and outcomes are published every half hour on the Pandemic Tracker Microsoft PowerBI dashboard. Supplementary dashboards track COVID-19 patient demographic and clinical data, cohort unit capacity, lab turnaround times, supply chain, PPE and medication inventory and demand.
- The RECOVER-19 Registry
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The AdventHealth Research Institute initiated a registry study to collect and disseminate clinical and laboratory data for research for all patients tested in the Central Florida Division. Soon to be expanded to the entire AdventHealth enterprise, the registry was developed under the IRB-approved protocol named “Registry and Biorepository of COVID-19 for AdventHealth Enterprise” (RECOVER-19 - AdventHealth IRBNet # 1590483). This protocol can support feasibility queries and is approved for data collection for the next five years.
RECOVER-19 is a real-world data (RWD) registry that includes clinical data on all patients tested for coronavirus disease 2019 (COVID-19) (both positive and negative) at AdventHealth CFD beginning January 1, 2020. The registry includes zip codes; demographic information; all personal medical history; and COVID-19 encounter clinical information such as type of encounter, length of stay, presenting symptoms, outcome, medication history during all inpatient visits and post-discharge, all procedures and diagnoses, and approximately 80 selected labs.