NCT05685004

Randomized controlled Phase 2b clinical trial to evaluate the safety and efficacy of TVI-Brain-1 combined with conformal radiotherapy and temozolomide compared to standard therapy as a treatment for newly diagnosed O6-methylguanine methyltransferase negative (MGMT unmethylated) grade 4 astrocytoma (glioblastoma multiforme; glioblastoma; GBM).

  • Enrollment

    This study is not currently enrolling.

  • Associated Conditions

  • Research Area

    Cancer Research

  • Principal Investigator

    Sherif Makar

  • Sponsor

    TVAX Biomedical Inc

This clinical trial is being performed because there is a need for safer and more effective treatments for glioblastomas. The purpose of this specific clinical study is to determine how safe and effective TVI-Brain-1 would be as a treatment for newly diagnosed glioblastomas when combined with surgery, radiotherapy and chemotherapy.