Elevating Weight-Loss Research for Greater Well-Being
To create a healthier community, our AdventHealth scientists and clinicians are working to discover how our genes, hormones, diet and activity affect our ability to burn calories and impact our appetites. By participating in an obesity research study or one of our weight-loss clinical trials, you can contribute to the greater good while enhancing your whole health and well-being, too.
You could be the breakthrough. Let us help you find a metabolism, obesity and weight-loss research study that’s right for you.
Featured Clinical Trials
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TRIPLE G: A Randomized, Double-Blind, Phase 1 Study to Investigate the Effect of LY3437943 versus Placebo on Calorie Intake and Energy Expenditure in Participants with Obesity Under Calorie Restriction
This study is currently enrolling.Research Area: Translational Research for Metabolism and DiabetesResearch Location: Orlando, FloridaStudy Purpose: The purposes of this study are to look at the effect of the study drug compared to placebo (a drug that looks like the study drug but has no active medicine) on calorie intake...
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COMET: ImpaCt Of shiftwork on METabolic Flexibility and Skeletal Muscle Clocks.
This study is currently enrolling.Research Area: Translational Research for Metabolism and DiabetesResearch Location: Orlando, FloridaStudy Purpose: To determine how working a nighttime shift impacts your metabolism.
To be enrolled in this study, you must meet certain requirements. You may be eligible to participate if you meet the...
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About Metabolism, Obesity and Weight-Loss Research
Read our answers to frequently asked questions about our research.
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Q:Question: What questions about metabolism, obesity and weight loss are researchers hoping to answer?
A:Answer:Our research efforts help us better understand:
Continue ReadingCollapse Answer- How do hormones and medicines change appetite and calorie burning?
- How does fat (adipose tissue) regulate metabolism?
- Which treatments or lifestyle changes effectively prevent or reverse obesity?
- How does the gut microbiome impact body weight?
- What characteristics define response to obesity treatments?
- How does obesity impact other metabolic conditions, such as non-alcoholic fatty liver disease (NAFLD)?
- How do different organs work individually or communicate with each other to impact obesity?
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Q:Question: What are the potential benefits of participating in a research study?
A:Answer:While research studies generally don’t benefit the study participants directly, participants are helping people who may have a particular disease in the future.
Some of our studies may provide personal benefits to you, such as:
Continue ReadingCollapse Answer- Weight loss or improvement in other health conditions
- Monetary incentives
- Access to new and advanced therapies and treatment strategies before they are available to the public
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Q:Question: What are the potential risks?
A:Answer:Some studies have risks associated with the treatments or procedures. Our medical providers screen every new potential participant to ensure they meet the criteria to safely participate.
Continue ReadingCollapse AnswerParticipation is voluntary, and our research team monitors participants' health and well-being during the length of the study. All risks are thoroughly explained, and we have strategies in place to minimize risk.
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Q:Question: What types of procedures are involved in metabolism, obesity and weight-loss research?
A:Answer:Our studies are all very different. Participants may be asked to:
Continue ReadingCollapse Answer- Take a medication
- Follow a diet or consume foods/supplements that we provide
- Undergo tissue and blood sampling
- Complete questionnaires
- Receive imaging such as MRI, DXA and PET-CT
- Wear an activity monitor
- Be measured for weight, height and waist circumference
- Stay in our clinical research unit for observation and procedures
- Have metabolism tested in our whole room calorimeters
- Exercise under supervision
Contact Us
You could be the breakthrough. Learn how you can help advance the future of health care. Join the AdventHealth Research Institute to help find the next cure.