Search our team at AdventHealth Research Institute
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MSBASE: An international registry dedicated to evaluating outcomes data in multiple sclerosis (MS) and other neuroimmunological diseases (NIDs)
This study is currently enrolling.Research Area: Neuroscience ResearchResearch Location: Orlando, FloridaThe MSBase Registry is a research registry. Research registries are also known as a research databases. They collect information about lots of people, often who all have the same health condition. The...
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NCT05147220
A randomized, double-blind, double-dummy, parallel-group study, comparing the efficacy and safety of remibrutinib versus teriflunomide in participants with relapsing multiple sclerosis, followed by extended treatment with open-label remibrutinib
This study is currently enrolling.Research Area: Neuroscience ResearchResearch Location: Orlando, FloridaThe main purpose of the study is to find out if patients treated with remibrutinib may experience fewer MS relapses (also called clinical attacks, exacerbations or flare ups) than patients treated...
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NCT05348785
A Phase 2b, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Determine the Efficacy and Safety of BIIB122 in Participants with Parkinson’s Disease
This study is currently enrolling.Associated Conditions: ParkinsonsResearch Area: Neuroscience ResearchResearch Location: Orlando, FloridaYou may be eligible to take part in the study because you have Parkinson’s Disease (PD). Only people who have been diagnosed with PD in the past 2 years and who are within the ages of 30 to 80 years...
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Isolation of Tumor Cells, Cancer Stem Cells and Human Neuronal Stem Cells from Human Brain Tumor Tissue for Analysis of Cancer Stem Cell Markers’ Expression in Cellular Differentiation and Self-renewal for Studying the Effectiveness of Cancer Therapy with Subsequent Identification of Exosomal Biomarkers for Early Diagnostic Purposes
This study is currently enrolling.Associated Conditions: Brain Diseases/CAResearch Area: Neuroscience ResearchResearch Location: Orlando, FloridaThe purpose of this clinical trial is to collect and study brain tumor samples to help understand why the tumor grows back and to seek new ways to treat it.
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NCT05766813
A Randomized, Double-blind, Placebo-controlled Multicenter Study to Assess the Efficacy and Safety of Lenrispodun as Adjunctive Therapy in the Treatment of Patients with Motor Fluctuations due to Parkinson’s Disease”
This study is not currently enrolling.Associated Conditions: ParkinsonsResearch Area: Neuroscience ResearchResearch Location: Orlando, FloridaThe purpose of this clinical research study is to look at an investigational study drug called lenrispodun. The study will investigate if lenrispodun can help to increase the time of good control of...
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NCT05626634
A Phase 2, multicenter, open-label, long-term safety study of LP352 in subjects with developmental and epileptic encephalopathy who completed Study LP352-201 and are candidates for continuous treatment for up to 52 weeks.
This study is not currently enrolling.Research Area: Neuroscience ResearchYou, or you and the individual you care for, are being asked to take part in a research study because you have seizures associated with developmental and epileptic encephalopathy (DEE) and you have...
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NCT05232929
LONG-TERM FOLLOW-UP STUDY OF PATIENTS WITH SPINAL MUSCULAR ATROPHY RECEIVING RISDIPLAM TREATMENT
This study is not currently enrolling.Associated Conditions: NeurodegenerativeResearch Area: Neuroscience ResearchResearch Location: Orlando, FloridaThe main purpose of this study is to follow patients receiving Evrysdi for a long time. This will add to the body of evidence about the safety and effectiveness of Evrysdi.
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NCT05064878
A Phase 3, Randomized, Double-blind, Placebo-Controlled, Fixed-Dose, Multicenter Study to Examine the Efficacy and Safety of ZX008 in Subjects with CDKL5 deficiency disorder followed by an Open-Label Extension.
This study is not currently enrolling.Associated Conditions: EpilepsyResearch Area: Neuroscience ResearchResearch Location: Orlando, FloridaThe purpose of this informed consent form is to collect data about the non-paid caregiver of a subject that is participating in ZX008-2103 study. You, as the non-paid caregiver, are being asked to...
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NCT05206773
A Randomized, Double-blind, Placebo-controlled, 12-month Phase 3 Study to Evaluate the Effect of Venglustat on Neuropathic and Abdominal Pain in Male and Female Adults with Fabry Disease who are Treatment-naïve or Untreated for At least 6 Months
This study is not currently enrolling.Research Area: Neuroscience ResearchResearch Location: Orlando, FloridaThe purpose of the study is to evaluate daily oral doses of the study drug called venglustat compared to placebo: what is the effectiveness (how well it works) on symptoms of the Fabry disease, mainly...
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NCT05076838
An Open-Label, Single-Dose, Pharmacokinetics Study of VALTOCO with Open-Label Safety Period in Pediatric Subjects with Epilepsy
This study is not currently enrolling.Associated Conditions: EpilepsyResearch Area: Neuroscience ResearchThis is a research study to evaluate the pharmacokinetics (PK), safety and tolerability after a single intranasal dose of VALTOCO (diazepam nasal spray), followed by a long-term safety period, where...