Search our team at AdventHealth Research Institute
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NCT04852887
A PHASE III CLINICAL TRIAL EVALUATING DE-ESCALATION OF BREAST RADIATION FOR CONSERVATIVE TREATMENT OF STAGE I, HORMONE SENSITIVE, HER2-NEGATIVE,ONCOTYPE RECURRENCE SCORE d 18 BREAST CANCER
This study is currently enrolling.Associated Conditions: Breast CancerResearch Area: Cancer ResearchResearch Location: Altamonte, FloridaThis study is being done to answer the following question: Is treatment with hormonal therapy as good as the usual treatment of radiation and hormonal therapy in women with low-risk breast cancer who...
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NCT03683186
ADVANCE OUTCOMES - A Study Evaluating the Efficacy and Safety of Ralinepag To Improve Treatment Outcomes in PAH Patients
This study is currently enrolling.Research Area: Heart, Lung and Vascular ResearchResearch Location: Orlando, FloridaA research study is a scientific way to improve or develop new methods of health care. Studies are designed to answer specific questions on how to prevent, diagnose, or treat diseases and disorders...
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Randomized Trial on Hybrid vs Non-Hybrid ESD for Colorectal Polyps
This study is currently enrolling.Research Area: Digestive Health and SurgeryResearch Location: Orlando, FloridaWe invite you to take part in a research study because you have colorectal polyp and are being treated here at AdventHealth Orlando. A clinical trial (research study) is done when researchers...
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NCT05194072
A Phase 1 Study of SGN-B7H4V in Advanced Solid Tumors
This study is currently enrolling.Associated Conditions: Multiple Tumor TypesResearch Area: Cancer Research -
NCT05348785
A Phase 2b, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Determine the Efficacy and Safety of BIIB122 in Participants with Parkinson’s Disease
This study is currently enrolling.Associated Conditions: ParkinsonsResearch Area: Neuroscience ResearchResearch Location: Orlando, FloridaYou may be eligible to take part in the study because you have Parkinson’s Disease (PD). Only people who have been diagnosed with PD in the past 2 years and who are within the ages of 30 to 80 years...
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NCT05093634
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study: 5 Independent Sub-studies of Setmelanotide in Patients with POMC, PCSK1, LEPR, SRC1, SH2B1, and PCSK1 N221D Gene Defects in the Melanocortin-4 Receptor Pathway
This study is currently enrolling.Research Area: Pediatrics ResearchResearch Location: Orlando, FloridaAppetite (feeling of hunger and feeling of being full after eating) and weight can be controlled by certain genes located in the brain. These genes are part of the Melanocortin-4-Receptor pathway...
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NCT04140526
Safety, Pharmacokinetics (PK), and Efficacy of ONC-392 as a Single Agent and in Combination with Pembrolizumab in Advanced Solid Tumors and NSCLC: An Open-label Phase IA/IB Study.
This study is currently enrolling.Associated Conditions: Multiple Tumor TypesResearch Area: Cancer ResearchResearch Location: Celebration, FloridaThis is a research study to find out if an experimental drug called ONC-392 is safe and effective in cancer patients and how the drug is absorbed and processed in the body of patients with cancer. ONC...
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NCT05064709
Assessment of Implantable CCM in the Heart Failure Group with Higher Ejection Fraction
This study is currently enrolling.Associated Conditions: Heart FailureResearch Area: Heart, Lung and Vascular ResearchResearch Location: Orlando, FloridaYour doctor has diagnosed you with HF. You are being asked to consider voluntary participation in a research study of CCM treatment with the Optimizer System, sponsored by Impulse Dynamics (USA) Inc...
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NCT04945460
A Phase 2, Double-blind, Randomized, Placebo-controlled Study to Evaluate the Effects of Sotatercept versus Placebo for the Treatment of Combined Postcapillary and Precapillary Pulmonary Hypertension (Cpc-PH) due to Heart Failure with Preserved Ejection Fraction (HFpEF)
This study is currently enrolling.Associated Conditions: Pulmonary HypertensionResearch Area: Heart, Lung and Vascular ResearchResearch Location: Orlando, FloridaYou are being asked to take part in a research study of an experimental treatment called
sotatercept. “Experimental” means that sotatercept is currently being tested and is not
approved for sale by... -
NCT05206773
A Randomized, Double-blind, Placebo-controlled, 12-month Phase 3 Study to Evaluate the Effect of Venglustat on Neuropathic and Abdominal Pain in Male and Female Adults with Fabry Disease who are Treatment-naïve or Untreated for At least 6 Months
This study is currently enrolling.Research Area: Neuroscience ResearchResearch Location: Orlando, FloridaThe purpose of the study is to evaluate daily oral doses of the study drug called venglustat compared to placebo: what is the effectiveness (how well it works) on symptoms of the Fabry disease, mainly...
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NCT03321734
INTERMITTENT HYPOXIA AND CAFFEINE IN INFANTS BORN PRETERM
This study is currently enrolling.Associated Conditions: NeonatalResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaYou are being asked to allow your baby to be in this research study because your premature baby was given the medication caffeine as treatment for his/her immature breathing in the neonatal intensive...
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NCT04245397
A Phase 1, Open-Label, Dose-Escalation with Expansion Study of SX-682 in Subjects with Myelodysplastic Syndrome Who Had Disease Progression or are Intolerant to Prior Therapy
This study is currently enrolling.Associated Conditions: Myelodysplastic SyndromeResearch Area: Cancer ResearchResearch Location: Orlando, FloridaThis research study is studying an investigational immunotherapy called SX-682 as a possible treatment for Myelodysplastic Syndrome.