Search our team at AdventHealth Research Institute
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NCT04321031
STARZL NETWORK FOR EXCELLENCE IN PEDIATRIC TRANSPLANTATION (snept) to improve the health of pediatric LIVER TRANSPLANT PATIENTS
This study is currently enrolling.Associated Conditions: Liver DiseaseResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaPediatric liver transplantation has become the standard of care for many children with liver diseases. However, different institutions often treat and manage children with liver transplant in...
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NCT05197920
DREAM: Diabetes RElated to Acute pancreatitis and its Mechanisms (DREAM). An observational cohort study from the Type 1 Diabetes in Acute Pancreatitis Consortium (T1DAPC)
This study is currently enrolling.Associated Conditions: Diabetes-Drug StudyResearch Area: Translational ResearchResearch Location: Orlando, FloridaStudy Purpose: The purpose of this research study is to find out how many people with acute pancreatitis develop diabetes. Risk factors for diabetes and the types of diabetes that occur after acute...
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NCT05046158
Randomized Clinical Trial to Compare Transforming Powder and Standard of Care Dressing Therapies to Heal Diabetic Foot Ulcers”
This study is currently enrolling.Research Area: Orthopedic ResearchYou are invited to take part in this research study because you have diabetes, are between the ages of eighteen (18) and eighty-nine (89) years old and have a diabetic foot ulcer (wound) for thirty...
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NCT04811092
HYPERION A Phase 3, Randomized, Doubleblind, Placebo-controlled Study to Evaluate Sotatercept When Added to Background Pulmonary Arterial Hypertension (PAH) Therapy in Newly Diagnosed Intermediate-and High-risk PAH Patients
This study is currently enrolling.Associated Conditions: Pulmonary HypertensionResearch Area: Heart, Lung and Vascular ResearchResearch Location: Orlando, FloridaPulmonary arterial hypertension (PAH) is a disease affecting the blood vessels of the lungs. PAH leads to increased pressure in the blood vessels of the lungs which further leads to straining of the...
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NCT04796337
SOTERIA - An Open-Label Long-Term Follow-Up Study to Evaluate the Effects of Sotatercept when Added to Background Pulmonary Arterial Hypertension (PAH) Therapy for the Treatment of PAH
This study is currently enrolling.Associated Conditions: Pulmonary HypertensionResearch Area: Heart, Lung and Vascular ResearchResearch Location: Orlando, FloridaWe are asking you to take part in this study because you are currently in a study with sotatercept and we want to find out if continuing to take sotatercept is safe and effective over a long period of...
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NCT04089358
StepByStep: A Randomized Trial of a Mobile Health and Social Media Physical Activity Intervention among Adolescent and Young Adult Childhood Cancer Survivors
This study is currently enrolling.Associated Conditions: Pediatric CancerResearch Area: Cancer ResearchResearch Location: Orlando, FloridaThe overall goals of this study are: (1) To compare the effect of 2 different physical activity programs on physical activity levels in adolescents and young adults who received and completed...
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NCT04226547
CATALYST - Clinical trial of atrial fibrillation patients comparing left atrial appendage occlusion therapy to non-vitamin K antagonist oral anticoagulants
This study is currently enrolling.Associated Conditions: CoagulationResearch Area: Heart, Lung and Vascular ResearchResearch Location: Orlando, FloridaThe purpose of this research study is to compare the safety and effectiveness of the Amulet device compared to non-vitamin K antagonist oral anticoagulants (NOACs) for ischemic stroke risk reduction....
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NCT04798261
STRIKE-PE: A Prospective, Multicenter Study of the Indigo Aspiration System Seeking to Evaluate the Long-Term Safety and Outcomes of Treating Pulmonary Embolism
This study is currently enrolling.Associated Conditions: Pulmonary EmbolismResearch Area: Heart, Lung and Vascular ResearchResearch Location: Orlando, FloridaYour study doctor has determined you have or have had a pulmonary embolism (PE). A PE is a blood clot in an artery or arteries in your lung. A clot can be life threatening if immediate action is not...
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NCT04807868
AVAIL: AdventHealth Research Institute Non-Alcoholic Fatty Liver Disease Biobank and Registry
This study is currently enrolling.Associated Conditions: Liver-NAFL, NASHResearch Area: Translational ResearchResearch Location: Orlando, FloridaNon-alcoholic fatty liver disease (NAFLD) is a common liver disease that leads to many health complications. Many people have this disease and do not know it. There are no medications available to...
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NCT04793958
A Randomized PHase 3 Study of MRTX849 in Combination with Cetuximab Versus Chemotherapy in Patients with Advanced Colorectal Cancer with KRAS G12C Mutation with Disease Progression On or After Standard First-Line Therapy
This study is currently enrolling.Associated Conditions: Colorectal CancerResearch Area: Cancer ResearchResearch Location: Orlando, FloridaThis is a study involving an investigational (experimental) drug called MRTX849, being developed by Mirati Therapeutics, Inc., which is the company that provides MRTX849 study drug and is funding and...
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NCT04754581
EXPET: Dynamic in vivo PET imaging and ex vivo biopsies from skeletal muscle and adipose tissue to investigate the effects of exercise on insulin resistance and mitochondrial energetics in type 2 diabetes
This study is currently enrolling.Associated Conditions: ExerciseResearch Area: Translational ResearchThe overall aim of this study is to investigate the effects of exercise training on skeletal muscle and adipose tissue insulin resistance in subjects with Type 2 Diabetes (T2D).
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NCT04457596
The CompassHER2 Trials (Comprehensive Use of Pathologic Response Assessment to Optimize Therapy in HER2-Positive Breast Cancer) CompassHER2 Residual Disease (RD), a Double-Blinded, Phase III Randomized Trial of T-DM1 Compared With T-DM1 and Tucatinib
This study is currently enrolling.Associated Conditions: Breast CancerResearch Area: Cancer ResearchResearch Location: Orlando, FloridaThis study is being done to answer the following question: Is the combination of T-DM1 and a newer drug tucatinib, better than usual treatment with T-DM1 alone at preventing your cancer from returning...