Search our team at AdventHealth Research Institute
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NCT02981628
A Phase 2 Study of INotuzumab Ozogamicin (NSC# 772518, IND #133494) in Children and Young Adults with Relapsed or Refractory CD22+ B-Acute Lymphoblastic Leukemia (B-ALL)
This study is currently enrolling.Associated Conditions: LeukemiaResearch Area: Cancer ResearchResearch Location: Orlando, FloridaThe overall goal of this study is to find out what effect, good and/or bad, the drug inotuzumab ozogamicin has on children and young adults with relapsed or refractory B-ALL.
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NCT04071327
PHAR - Pulmonary Hypertension Association Registry
This study is currently enrolling.Associated Conditions: Pulmonary HypertensionResearch Area: Heart, Lung and Vascular ResearchResearch Location: Orlando, FloridaWe are asking you to be included in the Pulmonary Hypertension Association (PHA) Registry (PHAR). This is a national project about people who have pulmonary hypertension (PH). We are asking you to...
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NCT03126916
A Phase 3 Study of 131I-Metaiodobenzylguanidine (131I-MIBG) or Crizotinib Added to Intensive Therapy for Children with Newly Diagnosed High-Risk Neuroblastoma
This study is currently enrolling.Associated Conditions: Brain CancerResearch Area: Cancer ResearchThe overall goals of this study are to: Compare the effects, good and/or bad, of the experimental drug 131I-MIBG added to current COG recommended therapy to the effects of current COG recommended...
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NCT03962543
A Phase 2b Trial of the MEK 1/2 Inhibitor (MEKi) PD-0325901 in Adult and Pediatric Patients with Neurofibromatosis Type 1 (NF1)-Associated Inoperable Plexiform Neurofibromas (PNs) that are Progressing or Causing Significant Morbidity
This study is currently enrolling.Associated Conditions: NeurofibromatosisResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaThis research is conducted to study an investigational drug referred to as PD-0325901 (also known as mirdametinib) that has not been approved by the US Food and Drug Administration (FDA) or any other...
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NCT00736749
Umbrella Long-Term Follow-Up Protocol
This study is currently enrolling.Associated Conditions: Companion StudyResearch Area: Cancer ResearchResearch Location: Orlando, FloridaThe overall goal of this study is to keep in contact with participants of COG clinical trials, so that up-to-date information will be available about these participants as they get older. This...
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NCT00898365
Renal Tumors Classification, Biology, and Banking Study
This study is currently enrolling.Associated Conditions: Kidney CancerResearch Area: Cancer ResearchResearch Location: Orlando, FloridaOver the past years, many studies have been done for children with kidney tumors. Each study done has increased what we know about these tumors and has helped doctors plan treatment for subjects with...
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NCT00097292
TRIALNET: Natural History Study of the Development of Type 1 Diabetes
This study is currently enrolling.Associated Conditions: Diabetes-MechanismsResearch Area: Translational ResearchResearch Location: Orlando, FloridaYou are being asked to be in a research study called the TrialNet Natural History Study of the Development of Type 1 Diabetes. As you know, TrialNet is an international research group dedicated to the...
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NCT03761446
REST: The role of type 2 diabetes on skeletal muscle atrophy and recovery following bed rest in older adults
This study is currently enrolling.Associated Conditions: Diabetes-Drug StudyResearch Area: Translational ResearchResearch Location: Orlando, FloridaStudy Purpose: To better understand the role of Type 2 Diabetes on skeletal muscle atrophy and recovery following bed rest.
Study Duration: 14 weeks
Study Commitment:
2 Screening Visits
5 Pre... -
NCT02521493
CIRB/COG AAML1531 Risk-stratified Therapy for Acute Myeloid Leukemia in Down Syndrome
This study is currently enrolling.Associated Conditions: Pediatric CancerResearch Area: Cancer ResearchResearch Location: Orlando, FloridaThe overall goals of this study are to: To find out if subjects with standard risk DS AML can be treated with less treatment and still have successful outcomes. To find out if subjects with high risk...
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NCT02402244
The Project: EveryChild Protocol: A Registry, Eligibility Screening, Biology and Outcome Study
This study is currently enrolling.Associated Conditions: Multiple Tumor TypesResearch Area: Cancer ResearchResearch Location: Orlando, FloridaWe are doing this study to find better ways to diagnose, treat and prevent cancers in children, adolescents and young adults. To do this, we need to learn more about cancers that happen to children...
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NCT03155620
NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) Screening Protocol Study Title for Study Participants: Pediatric MATCH screening protocol
This study is currently enrolling.Associated Conditions: Multiple Tumor TypesResearch Area: Cancer ResearchResearch Location: Orlando, FloridaThe main purpose of this study is to learn how well tumors that have specific genetic changes (mutations) respond to drugs that target those changes. This combination of a tumor with a mutation and a...
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Transoral Surgery Registry (TOS Registry)
This study is currently enrolling.Associated Conditions: Head and Neck CancerResearch Area: SurgeryA research registry is a database (data warehouse) where clinical and other related information from patients is collected and stored for medical research. The purpose of this TOS registry is to...