Search our team at AdventHealth Research Institute
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NCT03233711
A Randomized Phase II Study of Nivolumab after Combined Modality Therapy (CMT) in High Risk Anal Cancer
This study is not currently enrolling.Associated Conditions: Anal CancerResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThe purpose of this study is to find if adding the study drug, nivolumab (also known as OPDIVO), after standard chemotherapy {(mitomycin-C and 5-fluorouracil 5(-RU) or capecitabine) or 5-FU and...
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NCT03856099
A Multicenter, Open-Label, Phase Ⅱ Clinical Trial to Evaluate the Safety and Efficacy of TTAC-0001, a Fully Human Monoclonal Antibody in Patients with Recurrent Glioblastoma Progressed on Bevacizumab Including Therapy
This study is not currently enrolling.Associated Conditions: Brain CancerResearch Area: Clinical Cancer ResearchThe aim of this study is to assess the safety and effectiveness of the study drug, TTAC-0001 to patients with recurrent glioblastoma which has progressed on bevacizumab treatment. Another aim is to...
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NCT03126916
A Phase 3 Study of 131I-Metaiodobenzylguanidine (131I-MIBG) or Crizotinib Added to Intensive Therapy for Children with Newly Diagnosed High-Risk Neuroblastoma
This study is not currently enrolling.Associated Conditions: Brain CancerResearch Area: Clinical Cancer ResearchThe overall goals of this study are to: Compare the effects, good and/or bad, of the experimental drug 131I-MIBG added to current COG recommended therapy to the effects of current COG recommended...
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NCT00736749
Umbrella Long-Term Follow-Up Protocol
This study is not currently enrolling.Associated Conditions: Companion StudyResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThe overall goal of this study is to keep in contact with participants of COG clinical trials, so that up-to-date information will be available about these participants as they get older. This...
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Treatment of Bone Marrow Failure, Post Allogeneic Bone Marrow Transplant,w ith CD34+ Cell-Enriched Hematopoietic Stem Cell Infusion (Miltenyi Biotec's CliniMACS CD34 Reagent System) A HDE Treatment Protocol
This study is not currently enrolling.Associated Conditions: Multiple Tumor TypesResearch Area: Clinical Cancer Research[Shell Only] - HUD/CUD.
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NCT00898365
Renal Tumors Classification, Biology, and Banking Study
This study is not currently enrolling.Associated Conditions: Kidney CancerResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaOver the past years, many studies have been done for children with kidney tumors. Each study done has increased what we know about these tumors and has helped doctors plan treatment for subjects with...
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NCT02521493
CIRB/COG AAML1531 Risk-stratified Therapy for Acute Myeloid Leukemia in Down Syndrome
This study is not currently enrolling.Associated Conditions: Pediatric CancerResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThe overall goals of this study are to: To find out if subjects with standard risk DS AML can be treated with less treatment and still have successful outcomes. To find out if subjects with high risk...
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A Nanotechnology-Enabled Blood Test for Cancer Detection and Diagnosis
This study is not currently enrolling.Associated Conditions: Urothelial CancerResearch Area: Clinical Cancer ResearchThe purpose of this study is to determine if a new blood test can be used for early detection of prostate and kidney cancer. The results of this study may be published in a peer-reviewed scientific...
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NCT03279081
A Phase III, Randomized, Double Blind, Parallel Group, Placebo Controlled, International, Multicentre Study to Assess Efficacy and Safety of Cx601, Adult Allogeneic Expanded Adipose-Derived Stem Cells (eASC), for the Treatment of Complex Perianal Fistula(s) in Patients with Crohn's Disease Over a Period of 24 Weeks and a Follow-Up Period Up to 52 Weeks. ADMIRE-CD II Study.
This study is not currently enrolling.Associated Conditions: Inflammatory Bowel Disease (IBD)Research Area: Clinical Cancer ResearchThe purpose of this study is to confirm (1) how well the study drug works at a single dose of 120 million cells compared to a placebo; (2) how safe and tolerable the study drug is in patients with...
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NCT02367781
A Phase III, Multicenter, Randomized, Open-Label Study Evaluating the Efficacy and Safety of MPDl3280A (Anti−PD-L1 Antibody) In Combination with Carboplatin and Nab-Paclitaxel for Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non−Small Cell Lung Cancer
This study is not currently enrolling.Associated Conditions: Lung CancerResearch Area: Clinical Cancer Research[Abbreviated - Closed] The purpose of this study is to look at the effects, good or bad, of MPDL3280A on you and the specific type of lung cancer (non−small cell lung cancer [NSCLC]) from which you...
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PD-L1 expression in lung adenocarcinomas with different subtypes of KRAS mutations and its clinical significance
This study is not currently enrolling.Associated Conditions: Lung CancerResearch Area: Clinical Cancer ResearchThe purpose of this study is to evaluate if the degree of PD-L1 expression and/or certain subtype(s) of KRAS mutation which may impact outcomes (survivals and/or pattern of metastasis) of lung...