Search our team at AdventHealth Research Institute
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NCT02981628
A Phase 2 Study of INotuzumab Ozogamicin (NSC# 772518, IND #133494) in Children and Young Adults with Relapsed or Refractory CD22+ B-Acute Lymphoblastic Leukemia (B-ALL)
This study is currently enrolling.Associated Conditions: LeukemiaResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThe overall goal of this study is to find out what effect, good and/or bad, the drug inotuzumab ozogamicin has on children and young adults with relapsed or refractory B-ALL.
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NCT02402244
The Project: EveryChild Protocol: A Registry, Eligibility Screening, Biology and Outcome Study
This study is currently enrolling.Associated Conditions: Multiple Tumor TypesResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaWe are doing this study to find better ways to diagnose, treat and prevent cancers in children, adolescents and young adults. To do this, we need to learn more about cancers that happen to children...
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NCT01515787
A Phase II/III of Neoadjuvant FOLFOX with Selective Use of Combined Modality Chemoradiation versus Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection with Total Mesorectal Excision (PROSPECT)
This study is currently enrolling.Associated Conditions: Colorectal CancerResearch Area: Clinical Cancer ResearchResearch Location: Orlando, Florida[$] [Abbreviated - Closed] The purpose of this study is to compare the effects, both good and bad, of the standard treatment of chemotherapy and radiation to chemotherapy using a combination regimen...
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NCT05705401
A Phase III Randomized Trial of Radiotherapy Optimization for Low-Risk HER2-Positive Breast Cancer (HERO)
This study is not currently enrolling.Associated Conditions: Breast CancerResearch Area: Clinical Cancer Research -
CLEE011O12001 A phase IIIb study to characterize the effectiveness and safety of Adjuvant ribociclib in a wide patient population with HR+ HER2- early breast cancer (Adjuvant WIDER)
This study is not currently enrolling.Associated Conditions: Breast CancerResearch Area: Clinical Cancer Research -
A Randomized Phase 2b/Phase 3 Study of the TGF-β2 Targeting Antisense Oligonucleotide OT-101 in Combination with mFOLFIRINOX Compared with mFOLFIRINOX Alone in Patients with Advanced and Unresectable or Metastatic Pancreatic Cancer
This study is not currently enrolling.Associated Conditions: Colorectal CancerResearch Area: Clinical Cancer Research -
NCT04724018
DF/HCC 20-614 Combinations of Sacituzumab govitecan plus enfortumab vedotin and pembrolizumab for metastatic urothelial carcinoma: the Double Antibody Drug conjugate (DAD) and Double Antibody Drug Conjugate with Immunotherapy (DAD-IO) Phase I/II trial
This study is not currently enrolling.Associated Conditions: Urothelial CancerResearch Area: Clinical Cancer Research -
A global Phase 3, open label, Randomized Study of CB-010, a CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy vs the standard of care treatment in adult patients with high-risk, transplant-eligible Relapsed/Refractory Large B Cell Non-Hodgkin Lymphoma (ANTLER-Phase 3 [Part III])
This study is not currently enrolling.Associated Conditions: Bone CancerResearch Area: Clinical Cancer Research -
A Phase 2/3 randomized study of a Raludotatug Deruxtecan (R-DXd), a CDH6-directed Antibody-drug Conjugate, in Subjects with Platinum-resistant, High-grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancers
This study is not currently enrolling.Research Area: Clinical Cancer Research -
NCT06469944
A Phase 1/2 Open-Label, Umbrella Platform Design Study of Investigational Agents with Pembrolizumab (MK-3475) in Participants with Advanced Esophageal Cancer naïve to PD-1/PD-L1 Treatment [KEYMAKER-U06]
This study is not currently enrolling.Associated Conditions: Esophageal CancerResearch Area: Clinical Cancer Research -
Enzatamide plus Lutetium-PSMA as neoadjuvant therapy preceding radical prostatectomy for high risk localized/locally advanced prostate cancer: a Phase I/Ib trial
This study is not currently enrolling.Associated Conditions: Prostate CancerResearch Area: Clinical Cancer Research -
NCT05900908
A Randomized Controlled Trial of Surgical Resection with GammaTile Therapy and Adjuvant Systemic Therapy compared to Surgical Resection and Adjuvant Systemic Therapy at first recurrence in Glioblastoma.
This study is not currently enrolling.Associated Conditions: Brain CancerResearch Area: Clinical Cancer Research