Search our team at AdventHealth Research Institute
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NCT04722354
ABA: ABA-Abscisic Acid Effects on Glucose Homeostasis and Insulin Sensitivity
This study is not currently enrolling.Associated Conditions: Diabetes-Drug StudyResearch Area: Translational ResearchThe purpose of this study is to determine the effects of oral abscisic acid (ABA) on glucose metabolism in subjects with defined prediabetes.
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Mother Providing Recorded Voice to Her Preterm Infant in Incubator Improves Her Own Grief and Emotional Status
This study is not currently enrolling.Associated Conditions: NeonatalResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaStudies have shown that infants prefer the sound of their mother's voice above all others. After 2 weeks (or 14 days) of life, we would like to begin playing a recording to babies of their mother's...
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GluCog: Glycemic Variability and Fluctuations in Cognitive Status in Adults with Type I Diabetes
This study is not currently enrolling.Associated Conditions: Diabetes-MechanismsResearch Area: Translational ResearchThe purposes of this study is to understand how thinking, emotions, and blood glucose fluctuate over hours and days in people with type I diabetes.
Study Commitment: 1 Month
Aged ≥ 18 years
Sex: Male... -
NCT03926130
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo- and Active-Controlled, Treat-Through Study to Evaluate the Efficacy and Safety of Mirikizumab in Patients with Moderately to Severely Active Crohn's Disease.
This study is not currently enrolling.Associated Conditions: Inflammatory Bowel Disease (IBD)Research Area: Digestive Health and SurgeryThe main reason for you to take part in this study is not to treat you for your condition but to help in answering the following research questions:
How safe mirikizumab is and whether you might have... -
NCT04538261
Elevation of the Fetal Buttocks Prior to External Cephalic Version
This study is not currently enrolling.Associated Conditions: Neonatal, Care DeliveryResearch Area: Pediatrics ResearchIn this study, we will analyze the available NICU data to determine the predictive value of a Bronchopulmonary Dysplasia (BPD) scoring system. Later, we will determine a threshold score at which an...
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Prospective Registry for Colorectal Cancer: International Watch and Wait Database
This study is not currently enrolling.Associated Conditions: Colorectal CancerResearch Area: Cancer ResearchThis research is being done as part of a larger international database for 'Watch and Wait' rectal cancer patients. Currently, the 'Watch and Wait' treatment shows promising results worldwide, however...
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NCT03519945
A Phase 3, Multicenter, Open-Label Extension Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Patients with Moderately to Severely Active Ulcerative Colitis
This study is not currently enrolling.Associated Conditions: ColonResearch Area: Digestive Health and SurgeryResearch Location: Orlando, FloridaThis study is being done to help answer the following research questions: (a) How mirikizumab, an investigational drug, could help people with ulcerative colitis over time; (b) How safe long-term use...
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NCT04166409
A Phase 3 Randomized Non-Inferiority Study of Carboplatin and Vincristine versus Selumetinib (NSC# 748727, IND# 77782) in Newly Diagnosed or Previously Untreated Low-Grade Glioma (LGG) not associated with BRAFV600E Mutations or Systemic Neurofibromatosis Type 1 (NF1)
This study is not currently enrolling.Associated Conditions: Brain CancerResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaThis study looks at how well a drug called selumetinib works when given to children and young adults with LGG. The study doctors want to see if selumetinib works as well as CV for getting rid of or...
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NCT04284774
NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 subprotocol of Tipifarnib in Patients with Tumors Harboring HRAS Genomic Alterations
This study is not currently enrolling.Associated Conditions: Cancer, Multiple Tumor TypesResearch Area: Cancer ResearchResearch Location: Orlando, FloridaThis is a Phase 2 study of a study drug called tipifarnib. The main goal of the study is to find out what effect, good and/or bad effects the study drug tipifarnib may have on your tumor. A second...
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NCT04195555
APEC1621K NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of AG-120 (Ivosidenib) in Patients with Tumors Harboring IDH1 Mutations.
This study is not currently enrolling.Associated Conditions: Cancer, Multiple Tumor TypesResearch Area: Cancer ResearchResearch Location: Orlando, FloridaThe main goal is to find out what effect, good and/or bad effects AG-120 (ivosidenib) on your tumor. A second goal of the study is to evaluate side effects that might be caused by AG-120 (ivosidenib)...
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NCT04285658
Pediatric KIDney Stone (PKIDS) Care Improvement Network
This study is not currently enrolling.Associated Conditions: SurgeryResearch Area: Pediatrics ResearchThe purpose of this study is to improve the ability of pediatric patients and their caregivers to select surgical treatment options for kidney stones. The study also aims to help urologists use...
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NCT03871257
A Phase 3 Randomized Study of Selumetinib (IND# 77782) versus Carboplatin/Vincristine in Newly Diagnosed or Previously Untreated Neurofibromatosis Type 1 (NF1) Associated Low-Grade Glioma (LGG)
This study is not currently enrolling.Associated Conditions: Brain CancerResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaThe overall goals of this study are to see if selumetinib works just as well as the standard treatment of carboplatin/vincristine (CV) for subjects with NF1-associated LGG, and to see if selumetinib...