Search our team at AdventHealth Research Institute
-
NCT03220035
NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of Vemurafenib in Patients with Tumors Harboring BRAF V600 Mutations
This study is not currently enrolling.Associated Conditions: Cancer, All Tumor TypesResearch Area: Cancer ResearchResearch Location: Orlando, FloridaYou are being asked to participate in this study because you have relapsed or refractory tumor without a proven treatment strategy for cure. The main goal is to test any good and bad effects of the...
-
NCT03213652
NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of Ensartinib in Patients with Tumors Harboring ALK or ROSI Genomic Alterations
This study is not currently enrolling.Associated Conditions: Multiple Tumor TypesResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaYou are being asked to participate in this study because you have a relapsed or refractory tumor without a proven treatment strategy for cure. The main goal of this study is to test any good and bad...
-
NCT03213691
NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of Selumetinib (AZD6244 Hydrogen Sulfate)in Patients with Tumors Harboring Activating MAPK Pathway Mutations
This study is not currently enrolling.Associated Conditions: Multiple Tumor TypesResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaThe main goal is to test any good and bad effects of the study drug selumetinib (AZD6244 hydrogen sulfate) on your tumor. A second goal of the study is to evaluate side effects that might be caused by...
-
NCT03213678
NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of LY3023414 in Patients with Solid Tumors
This study is not currently enrolling.Associated Conditions: Cancer, Multiple Tumor TypesResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaThis is a Phase 2 study of a drug called LY3023414. In a Phase 2 study, the goal is to find out what effects, good and/or bad, a drug has on your tumor or type of cancer.
-
NCT02815891
TARGET-NASH: A 5-year Longitudinal Observational Study of Patients with Nonalcoholic Fatty Liver or Nonalcoholic Steatohepatitis
This study is not currently enrolling.Associated Conditions: Liver-NAFL, NASHResearch Area: Translational ResearchTARGET-NASH is a longitudinal observational cohort study of patients being managed for NASH or NAFL in clinical practice. TARGET-NASH will create a carefully maintained, actively monitored research...
-
NCT03574597
SELECT: Semaglutide Effects on Cardiovascular Outcomes in People With Overweight or Obesity
This study is not currently enrolling.Associated Conditions: Obesity-Drug StudyResearch Area: Translational ResearchSemaglutide is a medicine doctors can prescribe in some countries for the treatment of type 2 diabetes. A completed study showed that semaglutide reduced the risk of cardiovascular events (e.g. heart...
-
Using Ultrasound to Estimate Endotracheal Size at Sub-Cricoid Level in Extremely Preterm Infants
This study is not currently enrolling.Associated Conditions: NeonatalResearch Area: Pediatrics ResearchThe size of the endotracheal tube (ETT) is based on a baby's weight, not on the size of the trachea. This practice increases the risk of selecting an ETT that is inappropriately small and leads to sub...
-
NCT03324841
Caris Molecular Intelligence and Caris Centers of Excellence for Precision Medicine Network Outcomes Associated Repository
This study is not currently enrolling.Research Area: Cancer ResearchThe purpose of the research repository is to collect information, which will be used for research studies to evaluate how clinical outcomes relate to Caris Molecular INtelligence Services.
-
NCT03295734
ACES: Ace Inhibitors Combined with Exercise for Hypertensive Seniors
This study is not currently enrolling.Associated Conditions: Aging-Nutrition and Physical ActivityResearch Area: Translational ResearchResearch Location: Orlando, FloridaThe purpose of this research study is to see if regular exercise when combined with one of three commonly used high blood pressure medications can improve the physical abilities of older adults to...
-
NCT04168580
BATSR: BAT as a therapeutic for the metabolic and cardiac dysfunction with senescence
This study is not currently enrolling.Associated Conditions: ExerciseResearch Area: Translational ResearchTo be enrolled in this study, you must meet certain requirements. You may be eligible to participate if you meet the following criteria:
BMI ≤35 kg/m2
65-90 years of ageStudy Duration: Up to 120...
-
NCT03213704
NCI-COG Pediatric Match (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of LOXO-101 (Larotrectinib) in Patients with Tumors Harboring Actionable NTRK Fusions
This study is not currently enrolling.Associated Conditions: Cancer, Companion StudyResearch Area: Cancer ResearchResearch Location: Orlando, FloridaThe overall goal of this study is to test any good and bad effects of the study drug LOXO-101 (larotrectinib) on your tumor.
-
NCT04164966
HONEY: Development of novel biomarkers for the early diagnosis of type 1 diabetes
This study is not currently enrolling.Associated Conditions: Diabetes-MechanismsResearch Area: Translational ResearchResearch Location: Orlando, FloridaType 1 Diabetes (T1D) or Juvenile diabetes is an autoimmune disease projected to affect 5 million people, including 600,000 children in US alone, by the year 2050. There is currently no cure or...