Search our team at AdventHealth Research Institute
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NCT05264922
Stromal Vascular Fraction (SVF) Cells for Non-operative Treatment of Small Rotator Cuff Tears.
This study is not currently enrolling.Associated Conditions: Tendon InjuryResearch Area: Orthopedic ResearchThe purpose of the study is to compare the relative clinical efficacy of placebo injection with exercise program to SVF cell injection with Exercise program in patients with partial thickness Rotator...
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NCT05064878
A Phase 3, Randomized, Double-blind, Placebo-Controlled, Fixed-Dose, Multicenter Study to Examine the Efficacy and Safety of ZX008 in Subjects with CDKL5 deficiency disorder followed by an Open-Label Extension.
This study is not currently enrolling.Associated Conditions: EpilepsyResearch Area: Neuroscience ResearchResearch Location: Orlando, FloridaThe purpose of this informed consent form is to collect data about the non-paid caregiver of a subject that is participating in ZX008-2103 study. You, as the non-paid caregiver, are being asked to...
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MODIFY: A Case-Control, Observational, Proof of Mechanism Study to Define Microbiome-Mediated Gut Dysfunction Across the Spectrum of Non-Alcoholic Fatty Liver Disease.
This study is not currently enrolling.Associated Conditions: Liver-NAFL, NASHResearch Area: Translational ResearchThis study is being done to understand if the bacteria that are in your colon (the gut microbiome) get into the cells of the intestinal wall in people with fatty liver or fibrosis compared to people...
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NCT05046730
SEAM Trial: Sutureless End to End Anastomosis by Magnetic Compression: A Study to Evaluate Safety and Effectiveness of the GI Window’s Self-Forming Magnet (SFM) Anastomosis Device: A Historically Controlled Propensity Matched Study
This study is not currently enrolling.Research Area: Digestive Health and SurgeryYou are being asked to participate in this research study because you will be undergoing an ileostomy reversal surgery (also referred to as “ileostomy closure”). A reversal of ileostomy is an...
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NCT04137900
A First-in-Human, Multicenter, Open-Label, Phase 1 Dose-Escalation and Cohort Expansion Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TAB004 as Monotherapy and in Combination with Toripalimab in Subjects with Advanced Solid Malignancies including Lymphoma
This study is not currently enrolling.Associated Conditions: LymphomaResearch Area: Cancer ResearchThe purpose of this study is to determine the side effects of TAB004 (investigational drug) when given alone or in combination with toripalimab (another investigational drug), to determine a...
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NCT05258942
MyLeukoMAP Genomic Survival Prediction Assay
This study is not currently enrolling.Associated Conditions: Heart FailureResearch Area: TransplantHeart failure (HF) can cause other organs to shut down. This process appears to involve the white blood cells of the immune system. Our data show that abnormal gene activation or suppression of white...
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NCT03517332
Association of ctDNA and circulating tumor cells after neoadjuvant chemotherapy with disease recurrence in patients with advanced stage epithelial ovarian cancer, fallopian tube cancer, or primary peritoneal cancer.
This study is not currently enrolling.Associated Conditions: Ovarian, Fallopian, or Primary Peritoneum CancerResearch Area: Cancer ResearchTo compare the levels of ctDNA and CTCs using the SIGNATERA™ test in the peripheral blood of patients during neoadjuvant chemotherapy and after IDS for advanced stage epithelial ovarian carcinoma...
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NCT05027971
Multi-center, open label, prospective study to document on-going post market safety and performance of Flexiva Pulse High Power Single-Use Laser Fibers.
This study is not currently enrolling.Research Area: Digestive Health and SurgeryMulti-center, open label, prospective study to document on-going post market safety and performance of Flexiva Pulse High Power Single-Use Laser Fibers.
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Conservative Fluid Management in the First Week of Life Reduces the Risk of Prolonged Hemodynamically Significant Patent Ductus Arteriosus in Extremely Preterm Infants
This study is not currently enrolling.Research Area: Pediatrics ResearchResearch Location: Orlando, FloridaTo retrospectively collect and analyze the data to show that a change in practice at the Advent Health Orlando Neonatal Intensive Care Unit (NICU), implementing conservative fluid intake during the...
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Optune Lua for the treatment of adult patients with unresectable, locally advanced or metastatic, malignant pleural mesothelioma (MPM) to be used concurrently with pemetrexed and platinum-based chemotherapy
This study is not currently enrolling.Associated Conditions: Malignant Pleural MesotheliomaResearch Area: Cancer ResearchOptune Lua is indicated for the treatment of adult patients with unresectable, locally advanced or metastatic, malignant pleural mesothelioma (“MPM”) to be used concurrently with pemetrexed and...
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NCT05076838
An Open-Label, Single-Dose, Pharmacokinetics Study of VALTOCO with Open-Label Safety Period in Pediatric Subjects with Epilepsy
This study is not currently enrolling.Associated Conditions: EpilepsyResearch Area: Neuroscience ResearchThis is a research study to evaluate the pharmacokinetics (PK), safety and tolerability after a single intranasal dose of VALTOCO (diazepam nasal spray), followed by a long-term safety period, where...
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NCT05107856
A Phase 1, Open-Label, Multicenter, Dose Escalation Study of PRT1419 Injection in Patients with Relapsed/Refractory Hematologic Malignancies
This study is not currently enrolling.Associated Conditions: LeukemiaResearch Area: Cancer ResearchThe purpose of this research study is to test the safety of PRT1419 at different dose levels to find out what effects, good and/or bad, PRT1419 has on you and your type of cancer. The information...