Search our team at AdventHealth Research Institute
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PIONEER 4: A Study Investigating the Efficacy and Safety of Oral Semaglutide versus Liraglutide and versus Placebo in Subjects with Type 2 Diabetes Mellitus
This study is not currently enrolling.Research Area: Translational ResearchBefore a new medicine can be approved for use in humans, it is necessary to confirm that it is safe and effective. This is done by carrying out studies such as this one. The study product semaglutide...
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NCT01843127
GILEAD: A Phase 1, Randomized, Single-blind, Placebo-controlled, Multiple-dose, Two-sequence, Cross-over Study to Evaluate the Effect of Ranolazine on Glucagon Secretion in Subjects with Type 2 Diabetes Mellitus, Followed by An Open-label, Single-dose, Exenatide Active-control Period
This study is not currently enrolling.Research Area: Translational ResearchThe primary purpose of this study is to understand the reasons why Ranolazine may potentially treat patients with T2DM. Ranolazine has been shown to block glucagon and therefore results in a lowering...
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NCT02723994
A Phase 2 Study of the JAK1/JAK2 Inhibitor Ruxolitinib with Chemotherapy in Children with De Novo High-Risk CRLF2-Rearranged and/or JAK Pathway-Mutant Acute Lymphoblastic Leukemia
This study is not currently enrolling.Associated Conditions: LeukemiaResearch Area: Pediatrics ResearchThe overall goal of this study are to: Part 1 - Find the best dose of ruxolitinib to use with standard chemotherapy in children, adolescents, and young adults with HR B-ALL; Part 2 - Find out if the...
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VTEM PLASMA MARKERS - Plasma Biomarkers for Veno-ThromboEmbolic (VTE) Disease: Promise of Metabolomics (VTEM)
This study is not currently enrolling.Associated Conditions: Veno-Thromboembolic DiseaseResearch Area: Heart, Lung and Vascular ResearchWe invite you to take part in a research study because you have been diagnosed of having a blood clot in your body either in the legs called DVT deep vein thrombosis or possibly in your lungs called...
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Routine versus No Assessment of Gastric Residual Volumes in Very Low Birth Weight Infants Receiving Enteral Feeding via Intermittent Feeding Tubes: A Randomized Controlled Trial
This study is not currently enrolling.Associated Conditions: NeonatalResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaPre term infants require feeding tubes when they start receiving feeds. Once the volume of milk increases, the current practice in our Neonatal Intensive Care Unit (NICU) is to attach a syringe to the...
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Validation of the Pediatric Critical-care Pain Observation Tool (P-COPT) in PICU and Pediatric CVICU
This study is not currently enrolling.Research Area: Pediatrics ResearchThe specific aim of the proposed study is to further validate the P-CPOT in PICU and Pediatric CVICU ventilated patients who are 3 to 18 years.
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NCT04321031
Prospective Observational Study to Assess Outcomes in Pediatric Liver Transplant Recipients
This study is not currently enrolling.Associated Conditions: TransplantResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaThe purpose of the study is to collect scientific data on pediatric liver transplantation to learn more about how children do after liver transplant. Collecting this data is expected to help...
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Robotic-assisted Laparoscopic Varicocelectomy in the Pediatric population
This study is not currently enrolling.Associated Conditions: SurgeryResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaThe aim of this study is to describe outcomes and complications in robotic varicocelectomy in the pediatric population.
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Outcomes and Complications of Pediatric Robotic Ureteral Reimplantation
This study is not currently enrolling.Associated Conditions: SurgeryResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaThe aim of this to describe outcomes and complications in robotic ureteral reimplantation in the pediatric population.
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NCT03698994
NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of BVD-523FB (ulixertinib) in Patients with Tumors Harboring Activating MAPK Pathway Mutations
This study is not currently enrolling.Associated Conditions: Cancer, Multiple Tumor TypesResearch Area: Pediatrics ResearchYou are being asked to take part in this research study because your tumor results from the NCI-COG Pediatric MATCH screening protocol make you a candidate to receive the study drug called BVD-523FB...
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NCT03526250
NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of Palbociclib in Patients with Tumors Harboring Activating Alterations in Cell Cycle Genes
This study is not currently enrolling.Associated Conditions: Cancer, Multiple Tumor TypesResearch Area: Pediatrics ResearchThe main goal of this study is to test any good and bad effects of the palbociclib on your tumor. A second goal of the study is to evaluate side effects that might be caused by palbociclib.
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NCT03233204
NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of Olaparib in Patients with Tumors Harboring Defects in DNA Damage Repair Genes
This study is not currently enrolling.Associated Conditions: Cancer, All Tumor TypesResearch Area: Pediatrics ResearchThe main goal is to test any good and bad effects of the study drug olaparib on your tumor. A second goal of the study is to evaluate side effects that might be caused by olaparib and to learn more...