Search our team at AdventHealth Research Institute
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NCT03067181
A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients with Germ Cell Tumors
This study is not currently enrolling.Associated Conditions: Brain CancerResearch Area: Pediatrics ResearchResearch Location: Orlando, FloridaLow Risk Subjects (Age <50 Years): The overall goal is to see if monitoring subjects with low risk germ cell tumors after their tumor is removed is as effective as following surgery with chemotherapy...
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NCT04057677
RECOVER: Exercise training as an intervention to improve muscle function and Recovery following bed rest in older adults with type 2 diabetes
This study is not currently enrolling.Associated Conditions: Diabetes-Nutrition and Physical ActivityResearch Area: Translational ResearchThe purpose of this research is to gather data on how exercise can help recovery of muscle mass, strength, and physical function after bedrest. Procedures for this study include gathering medical...
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NCT04034706
EPIC: Transcriptomic and epigenetic characterization of the subcutaneous fat depots in PCOS women
This study is not currently enrolling.Associated Conditions: Polycystic Ovary SyndromeResearch Area: Translational ResearchPolycystic ovary syndrome, or PCOS, is a hormonal condition where your reproductive hormones are out of balance. PCOS is also associated with an increased risk to become obese and a male-like fat...
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NCT03233711
A Randomized Phase II Study of Nivolumab after Combined Modality Therapy (CMT) in High Risk Anal Cancer
This study is not currently enrolling.Associated Conditions: Anal CancerResearch Area: Cancer ResearchResearch Location: Orlando, FloridaThe purpose of this study is to find if adding the study drug, nivolumab (also known as OPDIVO), after standard chemotherapy {(mitomycin-C and 5-fluorouracil 5(-RU) or capecitabine) or 5-FU and...
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NCT03856099
A Multicenter, Open-Label, Phase Ⅱ Clinical Trial to Evaluate the Safety and Efficacy of TTAC-0001, a Fully Human Monoclonal Antibody in Patients with Recurrent Glioblastoma Progressed on Bevacizumab Including Therapy
This study is not currently enrolling.Associated Conditions: Brain CancerResearch Area: Cancer ResearchThe aim of this study is to assess the safety and effectiveness of the study drug, TTAC-0001 to patients with recurrent glioblastoma which has progressed on bevacizumab treatment. Another aim is to...
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NCT03960827
MoTrPAC: Molecular Transducers of Physical Activity Consortium
This study is not currently enrolling.Associated Conditions: ExerciseResearch Area: Translational ResearchResearch Location: Orlando, FloridaThe goal of the Molecular Transducers of Physical Activity Consortium (MoTrPAC) is to assess molecular changes that occur in response to physical activity (PA). To achieve this aim, a mechanistic...
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MATPET: Dynamic PET imaging in skeletal muscle and adipose tissue to explore mechanisms of peripheral glucose uptake in African American, Hispanic, and Caucasian Women
This study is not currently enrolling.Associated Conditions: Diabetes-MechanismsResearch Area: Translational ResearchStudy Purpose: The objective of this study is to obtain a better understanding between skeletal muscle characteristics and the ability to metabolize glucose. AdventHealth is seeking African American...
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Treatment of Bone Marrow Failure, Post Allogeneic Bone Marrow Transplant,w ith CD34+ Cell-Enriched Hematopoietic Stem Cell Infusion (Miltenyi Biotec's CliniMACS CD34 Reagent System) A HDE Treatment Protocol
This study is not currently enrolling.Associated Conditions: Multiple Tumor TypesResearch Area: Cancer Research[Shell Only] - HUD/CUD.
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A Nanotechnology-Enabled Blood Test for Cancer Detection and Diagnosis
This study is not currently enrolling.Associated Conditions: Urothelial CancerResearch Area: Cancer ResearchThe purpose of this study is to determine if a new blood test can be used for early detection of prostate and kidney cancer. The results of this study may be published in a peer-reviewed scientific...
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NCT03279081
A Phase III, Randomized, Double Blind, Parallel Group, Placebo Controlled, International, Multicentre Study to Assess Efficacy and Safety of Cx601, Adult Allogeneic Expanded Adipose-Derived Stem Cells (eASC), for the Treatment of Complex Perianal Fistula(s) in Patients with Crohn's Disease Over a Period of 24 Weeks and a Follow-Up Period Up to 52 Weeks. ADMIRE-CD II Study.
This study is not currently enrolling.Associated Conditions: Inflammatory Bowel Disease (IBD)Research Area: Cancer ResearchThe purpose of this study is to confirm (1) how well the study drug works at a single dose of 120 million cells compared to a placebo; (2) how safe and tolerable the study drug is in patients with...
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NCT01936948
Endoscopic resection of large colorectal polyps: An observational cohort study (Large Polyp Study group, study III)
This study is not currently enrolling.Associated Conditions: ColonResearch Area: Digestive Health and SurgeryThe primary aim of the study is to examine the rate of complications, complete polyp resection, and polyp recurrence during 5 years of follow-up. The secondary aim of the study is examine factors...
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NCT02367781
A Phase III, Multicenter, Randomized, Open-Label Study Evaluating the Efficacy and Safety of MPDl3280A (Anti−PD-L1 Antibody) In Combination with Carboplatin and Nab-Paclitaxel for Chemotherapy-Naïve Patients with Stage IV Non-Squamous Non−Small Cell Lung Cancer
This study is not currently enrolling.Associated Conditions: Lung CancerResearch Area: Cancer Research[Abbreviated - Closed] The purpose of this study is to look at the effects, good or bad, of MPDL3280A on you and the specific type of lung cancer (non−small cell lung cancer [NSCLC]) from which you...