Search our team at AdventHealth Research Institute
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NCT03295734
ACES: Ace Inhibitors Combined with Exercise for Hypertensive Seniors
This study is not currently enrolling.Associated Conditions: Aging-Nutrition and Physical ActivityResearch Area: Translational Research for Metabolism and DiabetesResearch Location: Orlando, FloridaThe purpose of this research study is to see if regular exercise when combined with one of three commonly used high blood pressure medications can improve the physical abilities of older adults to...
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NCT04168580
BATSR: BAT as a therapeutic for the metabolic and cardiac dysfunction with senescence
This study is not currently enrolling.Associated Conditions: ExerciseResearch Area: Translational Research for Metabolism and DiabetesTo be enrolled in this study, you must meet certain requirements. You may be eligible to participate if you meet the following criteria:
BMI ≤35 kg/m2
65-90 years of ageStudy Duration: Up to 120...
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NCT03213704
NCI-COG Pediatric Match (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of LOXO-101 (Larotrectinib) in Patients with Tumors Harboring Actionable NTRK Fusions
This study is not currently enrolling.Associated Conditions: Cancer, Companion StudyResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThe overall goal of this study is to test any good and bad effects of the study drug LOXO-101 (larotrectinib) on your tumor.
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NCT04164966
HONEY: Development of novel biomarkers for the early diagnosis of type 1 diabetes
This study is not currently enrolling.Associated Conditions: Diabetes-MechanismsResearch Area: Translational Research for Metabolism and DiabetesResearch Location: Orlando, FloridaType 1 Diabetes (T1D) or Juvenile diabetes is an autoimmune disease projected to affect 5 million people, including 600,000 children in US alone, by the year 2050. There is currently no cure or...
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NCT03067181
A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients with Germ Cell Tumors
This study is not currently enrolling.Associated Conditions: Brain CancerResearch Area: Pediatric Research and Clinical TrialsResearch Location: Orlando, FloridaLow Risk Subjects (Age <50 Years): The overall goal is to see if monitoring subjects with low risk germ cell tumors after their tumor is removed is as effective as following surgery with chemotherapy...
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NCT04057677
RECOVER: Exercise training as an intervention to improve muscle function and Recovery following bed rest in older adults with type 2 diabetes
This study is not currently enrolling.Associated Conditions: Diabetes-Nutrition and Physical ActivityResearch Area: Translational Research for Metabolism and DiabetesThe purpose of this research is to gather data on how exercise can help recovery of muscle mass, strength, and physical function after bedrest. Procedures for this study include gathering medical...
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NCT04034706
EPIC: Transcriptomic and epigenetic characterization of the subcutaneous fat depots in PCOS women
This study is not currently enrolling.Associated Conditions: Polycystic Ovary SyndromeResearch Area: Translational Research for Metabolism and DiabetesPolycystic ovary syndrome, or PCOS, is a hormonal condition where your reproductive hormones are out of balance. PCOS is also associated with an increased risk to become obese and a male-like fat...
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NCT03233711
A Randomized Phase II Study of Nivolumab after Combined Modality Therapy (CMT) in High Risk Anal Cancer
This study is not currently enrolling.Associated Conditions: Anal CancerResearch Area: Clinical Cancer ResearchResearch Location: Orlando, FloridaThe purpose of this study is to find if adding the study drug, nivolumab (also known as OPDIVO), after standard chemotherapy {(mitomycin-C and 5-fluorouracil 5(-RU) or capecitabine) or 5-FU and...
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NCT03856099
A Multicenter, Open-Label, Phase Ⅱ Clinical Trial to Evaluate the Safety and Efficacy of TTAC-0001, a Fully Human Monoclonal Antibody in Patients with Recurrent Glioblastoma Progressed on Bevacizumab Including Therapy
This study is not currently enrolling.Associated Conditions: Brain CancerResearch Area: Clinical Cancer ResearchThe aim of this study is to assess the safety and effectiveness of the study drug, TTAC-0001 to patients with recurrent glioblastoma which has progressed on bevacizumab treatment. Another aim is to...
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NCT03960827
MoTrPAC: Molecular Transducers of Physical Activity Consortium
This study is not currently enrolling.Associated Conditions: ExerciseResearch Area: Translational Research for Metabolism and DiabetesResearch Location: Orlando, FloridaThe goal of the Molecular Transducers of Physical Activity Consortium (MoTrPAC) is to assess molecular changes that occur in response to physical activity (PA). To achieve this aim, a mechanistic...
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MATPET: Dynamic PET imaging in skeletal muscle and adipose tissue to explore mechanisms of peripheral glucose uptake in African American, Hispanic, and Caucasian Women
This study is not currently enrolling.Associated Conditions: Diabetes-MechanismsResearch Area: Translational Research for Metabolism and DiabetesStudy Purpose: The objective of this study is to obtain a better understanding between skeletal muscle characteristics and the ability to metabolize glucose. AdventHealth is seeking African American...
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Treatment of Bone Marrow Failure, Post Allogeneic Bone Marrow Transplant,w ith CD34+ Cell-Enriched Hematopoietic Stem Cell Infusion (Miltenyi Biotec's CliniMACS CD34 Reagent System) A HDE Treatment Protocol
This study is not currently enrolling.Associated Conditions: Multiple Tumor TypesResearch Area: Clinical Cancer Research[Shell Only] - HUD/CUD.